9/11: Flight 93 attacks Pittsburgh

In this scenario, the passengers try to take control of the plane maybe 10 or 20 minutes earlier or later. Maybe a flight is delayed or something. As a result, the terrorists realize their mission is in jeopardy...but they're not that far from Pittsburgh.

They figure: well, if we're not going to be able to make the White House anyway, might as well wreck Pittsburgh. So they do whatever maneuver triggered the crash IOTL and aim for a building. You choose the target.
 
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